業績

2007年

原著論文

• "Analysis of fluctuation in protein abundance without promoter regulation based on Escherichia coli continuous culture"
  Tadashi Yamada, Chikara Furusawa, Keisuke Nagahisa, Akiko Kashiwagi, Tetsuya Yomo, Hiroshi Shimizu
  Biosystems 90, 3, 614-622 (2007).
• "Metabolic pathway rerouting through genomic data analysis for industrial application of Saccharomyces cerevisiae"
  Suteaki Shioya, Hiroshi Shimizu, Takashi Hirasawa, Keisuke Nagahisa, Chikara Furusawa, Gaurav Pandey, Yoshio Katakura
  Biochemical Engineering Journal 36, 1, 28-37 (2007).
• "Direct measurement of isotopomer of intracellular metabolites using capillary electrophoresis time-of-flight mass spectrometry for efficient metabolic flux analysis"
  Yoshihiro Toya, Nobuyoshi Ishii, Takashi Hirasawa, Miki Naba, Kenta Hirai, Kaori Sugawara, Saori Igarashi, Kazuyuki Shimizu, Masaru Tomita, Tomoyoshi Soga
  Journal of Chromatography 1159, 134-141 (2007).
• "Reduction of lactate production in Lactococcus lactis, a combined strategy: metabolic engineering by introducing the foreign alanine dehydrogenase gene and hemin addition"
  Agustin Krisna Wardani, Keisuke Nagahisa, Hiroshi Shimizu, Suteaki Shioya
  World Journal of Microbiology and Biotechnology 23, 7, 947-953 (2007).
• "Identification of target genes for conferring ethanol stress-tolerance to yeast Saccharomyces cerevisiae based on DNA microarray data analysis"
  Takashi Hirasawa, Katsunori Yoshikawa, Yuki Nakakura, Keisuke Nagahisa, Chikara Furusawa, Yoshio Katakura, Hiroshi Shimizu, Suteaki Shioya
  Journal of Biotechnology 131, 1, 34-44 (2007).
• "Study on roles of anaplerotic pathways in glutamate overproduction of Corynebacterium glutamicum by metabolic flux analysis"
  Tomokazu Shirai, Koki Fujimura, Chikara Furusawa, Keisuke Nagahisa, Suteaki Shioya, Hiroshi Shimizu
  Microbial Cell Factories 6, 1, 44731 (2007).
• "Analysis of hemin effect on lactate reduction in Lactococcus lactis"
  Machiko Nagayasu, Agustin Krisna Wardani, Keisuke Nagahisa, Hiroshi Shimizu, Suteaki Shioya
  Journal of Bioscience and Bioengineering 103, 6, 529-534 (2007).
• "Physiological analysis of yeast cells by flow cytometry during serial-repitching of low-malt beer fermentation"
  Michiko Kobayashi, Hiroshi Shimizu, Suteaki Shioya,
  Journal of Bioscience and Bioengineering 103, 5, 451-456 (2007).
• "Extracting hidden features in saline osmotic tolerance in Saccharomyces cerevisiae from DNA microarray data using self- organizing map: biosynthesis of amino acids"
  Gaurav Pandey, Katsunori Yoshikawa, Takashi Hirasawa, Keisuke Nagahisa, Yoshio Katakura, Chikara Furusawa, Hiroshi Shimizu, Suteaki Shioya
  Applied Microbiology and Biotechnology 75, 2, 415-426 (2007).
• "Kinetic modeling of kefiran production in mixed culture of Lactobacillus kefiranofaciens and Saccharomyces cerevisiae"
  Benjamas Cheirsilp, Hiroshi Shimizu, Suteaki Shioya
  Process Biochemistry 42, 4, 570-579 (2007).
• "Multiple high throughput analyses monitor the response of E. coli to perturbations"
  Nobuyoshi Ishii, Kenji Nakahigashi, Tomoya Baba, Martin Robert, Tomoyoshi Soga, Akio Kanai, Takashi Hirasawa, Miki Naba, Kenta Hirai, Aminul Hoque, Pei Yee Ho, Yuji Kakazu, Kaori Sugawara, Saori Igarashi, Satoshi Harada, Takeshi Masuda, Naoyuki Sugiyama, Takashi Togashi, Miki Hasegawa, Yuki Takai, Katsuyuki Yugi, Kazuharu Arakawa, Nayuta Iwata, Yoshihiro Toya, Yoichi Nakayama, Takaaki Nishioka, Kazuyuki Shimizu, Hirotada Mori, Masaru Tomita
  Science 316, 5824, 593-597 (2007).

総説､解説

• "バイオ情報工学の展開"
  清水 浩
  ソフトウエアバイオロジー 6, 3月7日 (2007).

学位論文

• "コリネ型細菌のグルタミン酸生産における代謝解析に関する研究"
  白井 智量
  (2007).

著書

• "Production of glutamate and glutamate-related amino acids: molecular mechanism analysis and metabolic engineering, Amino Acid Biosynthesis – Pathways, Regulation and Metabolic Engineering"
  Hiroshi Shimizu, Takashi Hirasawa
  Microbiology Monographs (Springer) 5, 1-38 (2007).