業績

2012年

原著論文

• "Molecular Mechanisms and Metabolic Engineering of Glutamate Overproduction in Corynebacterium glutamicum"
  Takashi Hirasawa, Jongpill Kim, Tomokazu Shirai, Chikara Furusawa, Hiroshi Shimizu
  Reprogramming Microbial Metabolic Pathways 64, 261-281 (2012).
• "Systems Metabolic Engineering: The Creation of Microbial Cell Factories by Rational Metabolic Design and Evolution"
  Chikara Furusawa, Takaaki Horinouchi, Takashi Hirasawa, Hiroshi Shimizu
  Advances in biochemical engineering/biotechnology 131, 44584 (2012).
• "An in silico platform for the design of heterologous pathways in nonnative metabolite production"
  Sunisa Chatsurachai, Chikara Furusawa, Hiroshi Shimizu
  BMC Bioinformatics 13, 1, 93 (2012).
• "Investigating the effects of perturbations to pgi and eno gene expression on central carbon metabolism in Escherichia coli using 13C metabolic flux analysis"
  Yuki Usui, Takashi Hirasawa, Chikara Furusawa, Tomokazu Shirai, Natsuko Yamamoto, Hirotada Mori, Hiroshi Shimizu
  Microbial Cell Factories 11, 1, 87 (2012).
• "Metabolic regulation analysis of wild-type and arcA mutant Escherichia coli under nitrate conditions using different levels of omics data"
  Yoshihiro Toya, Kenji Nakahigashi, Masaru Tomita, Kazuyuki Shimizu
  Molecular BioSystems 8, 10, 2593-2604 (2012).
• "Understanding the mechanism of heat stress tolerance caused by high trehalose accumulation in Saccharomyces cerevisiae using DNA microarray"
  Siraje Arif Mahmud, Takashi Hirasawa, Chikara Furusawa, Katsunori Yoshikawa, Hiroshi Shimizu
  Journal of Bioscience and Bioengineering 113, 4, 526-528 (2012).
• "Stable disruption of ethanol production by deletion of the genes encoding alcohol dehydrogenase isozymes in Saccharomyces cerevisiae"
  Yoshihiro Ida, Chikara Furusawa, Takashi Hirasawa, Hiroshi Shimizu
  Journal of Bioscience and Bioengineering 113, 2, 192-195 (2012).

総説､解説

• "光合成微生物システムバイオロジー"
  吉川 勝徳, 古澤 力, 平沢 敬, 清水 浩
  生物工学会誌 90, 10, 627-628 (2012).
• "代謝工学の創成と発展、-代謝解析とオミクス研究との融合"
  清水 浩, 古澤 力, 平沢 敬, 吉川 勝徳, 小野 直亮, 戸谷 吉博, 白井 智量
  生物工学会誌 90, 10, 619-620 (2012).
• "Differential importance of trehalose accumulation in Saccharomyces cerevisiae in response to various environmental stresses (出芽酵母における複数の環境ストレスに対するトレハロース蓄積の効果の差異)"
  Siraje Arif Mahmud, 平沢敬, 清水浩
  生物工学会誌 90, 2, 80 (2012).

著書

• "Systems metabolic engineering: the creation of microbial cell factories by rational metabolic design and evolution"
  Chikara Furusawa, Takaaki Horinouchi, Takashi Hirasawa, Hiroshi Shimizu
  Advanced Biochemical Engineering/Biotechnology (Springer), 1-23 (2012).
• "Molecular mechanisms and metabolic engineering of glutamate overproduction in Corynebacterium glutamicum (Springer)"
  Takashi Hirasawa, Jongpill Kim, Tomokazu Shirai, Chikara Furusawa, Hiroshi Shimizu
  Subcellular Biochemistry Vol. 64, Reprogramming Microbial Metabolic Pathways (Springer), 261-281 (2012).
• "Chapter3, Design of Superior Cell Factories Based on Systems Wide Omics Analysis"
  Katsunori Yoshikawa, Chikara Furusawa, Takashi Hirasawa, Hiroshi Shimizu
  Systems Metabolic Engineering (Springer), 57-82 (2012).
• "第2節　ゲノムスケール代謝デザインとフラックス解析による微生物細胞創製"
  清水 浩, 古澤 力, 白井 智量, 吉川 勝徳, 平沢 敬
  合成生物工学の隆起 ―有用物質の新たな生産法構築をめざして― 第3章 オミクス解析の視点 (シーエムシー出版), 57-66 (2012).
• "第12章 ゲノム・生物情報工学"
  清水 浩
  遺伝子工学 (化学同人), 170-181 (2012).