業績

2013年

原著論文

• "A vector library for silencing central carbon-metabolism genes with antisense RNAs in Escherichia coli."
  Nobutaka Nakashima, Satoshi Ohno, Katsunori Yoshikawa, Hiroshi Shimizu, Tomohiro Tamura
  Applied and Environmental Microbiology 80, 2, 564-73 (2013).
• "ArtPathDesign -Rational heterologous pathway design system for the production of　nonnative metabolites"
  Sunisa Chatsurachai, Chikara Furusawa, Hiroshi Shimizu
  Journal of Bioscience and Bioengineering 116, 4, 524-527 (2013).
• "Genome-wide identification of the targets for genetic manipulation to improve L-lactate production by Saccharomyces cerevisiae by using a single-gene deletion strain collection"
  Takashi Hirasawa, Masakado Takekuni, Katsunori Yoshikawa, Aki Ookubo, Chikara Furusawa, Hiroshi Shimizu
  Journal of Biotechnology 168, 2, 185-193 (2013).
• "Time-resolved metabolomics of a novel trebouxiophycean alga using 13CO2 feeding"
  Takuro Ito, Masahiro Sugimoto, Yoshihiro Toya, Yoshitaka Ano, Norihide Kurano, Tomoyoshi Soga, Masaru Tomita
  Journal of Bioscience and Bioengineering 116, 3, 408-415 (2013).
• "Integrated transcriptomic and metabolomic analysis of the central metabolism of Synechocystis sp. PCC 6803 under different trophic conditions"
  Katsunori Yoshikawa, Takashi Hirasawa, Kenichi Ogawa, Yuki Hidaka, Tsubasa Nakajima, Chikara Furusawa, Hiroshi Shimizu
  Biotechnology Journal 8, 5, 513-514 (2013).
• "Utilization of Saccharomyces cerevisiae recombinant strain incapable of both ethanol and glycerol biosynthesis for anaerobic bioproduction"
  Yoshihiro Ida, Takashi Hirasawa, Chikara Furusawa, Hiroshi Shimizu
  Applied Microbiology and Biotechnology 97, 11, 4811-4819 (2013).
• "Development of a physical model-based algorithm for the detection of single-nucleotide substitutions by using tiling microarrays"
  Naoaki Ono, Shingo Suzuki, Chikara Furusawa, Hiroshi Shimizu, Tetsuya Yomo
  PLoS One 8, 1, e54571 (2013).
• "In silico screening of triple reaction knockout Escherichia coli strains for overproduction of useful metabolites"
  Satoshi Ohno, Chikara Furusawa, Hiroshi Shimizu
  Journal of Bioscience and Bioengineering 115, 2, 221-228 (2013).
• "Systems metabolic engineering for the production of bio‐nylon precursor"
  Hiroshi Shimizu
  Biotechnology Journal 8, 5, 513-514 (2013).
• "Flux analysis and metabolomics for systematic metabolic engineering of microorganisms"
  Yoshihiro Toya, Hiroshi Shimizu
  Biotechnology Advances 31, 6, 818-826 (2013).
• "Potential of a Saccharomyces cerevisiae recombinant strain lacking ethanol and glycerol biosynthesis pathways in efficient anaerobic bioproduction"
  Takashi Hirasawa, Yoshihiro Ida, Chikara Furuasawa, Hiroshi Shimizu
  Bioengineered 5, 3, 123-128 (2013).

総説､解説

• "生命現象の数理表現と生命システムデザイン"
  清水 浩
  生物工学会誌 91, 12, 712-716 (2013).
• "Flux analysis and metabolomics for systematic metabolic engineering of microorganisms"
  Toya Yoshihiro, Shimizu Hiroshi
  Biotechnology Advances 31, 6, 818-826 (2013).

学位論文

• "出芽酵母を用いた物質生産のための代謝設計に関する研究"
  井田 祥弘
  (2013).
• "Development of computational method for heterologous pathways design"
  Sunisa Chatsurachai
  (2013).
• "遊離アミノ酸および中間代謝物質の13C標識情報に基づく代謝フラックス解析に関する研究"
  森 英詞
  (2013).