業績

2016年

原著論文

• "Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer"
  Miyo Masaaki, Konno Masamitsu, Nishida Naohiro, Sueda Toshinori, Noguchi Kozo, Matsui Hidetoshi, Colvin Hugh, Kawamoto Koichi, Koseki Jun, Haraguchi Naotsugu, Nishimura Junichi, Hata Taishi, Gotoh Noriko, Matsuda Fumio, Satoh Taroh, Mizushima Tsunekazu, Shimizu Hiroshi, Doki Yuichiro, Mori Masaki, Ishii Hideshi
  Scientific Reports 6, 38415 (2016).
• "Combinatorial deletions of glgC and phaCE enhance ethanol production in Synechocystis sp. PCC 6803"
  Katsunori Namakoshi, Tubasa Nakajima, Katsunori Yoshikawa, Yoshihiro Toya, Hiroshi Shimizu
  Journal of Biotechnology 239, -, 13-19 (2016).
• "13C-metabolic flux analysis for mevalonate producing Escherichia coli"
  Keisuke Wada, Yoshihiro Toya, Satomi Banno, Katsunori Yoshikawa, Fumio Matsuda, Hiroshi Shimizu
  Journal of Bioscience and Bioengineering 123, 2, 177-182 (2016).
• "Positive effects of proline addition on the central metabolism of wild-type and lactic acid-producing Saccharomyces cerevisiae strains"
  Riyanto Heru Nugroho, Katsunori Yoshikawa, Fumio Matsuda, Hiroshi Shimizu
  Bioprocess and Biosystems Engineering 39, 11, 1711-1716 (2016).
• "GC-MS/MS survey of collision-induced dissociation of tert-butyldimethylsilyl-derivatized amino acids and its application to 13C -metabolic flux analysis of Escherichia coli central metabolism"
  Nobuyuki Okahashi, Shuichi Kawana, Junko Iida, Hiroshi Shimizu, Fumio Matsuda
  Analytical and Bioanalytical Chemistry 408, 22, 6133-6140 (2016).
• "Investigation of useful carbon tracers for 13C-metabolic flux analysis of Escherichia coli by considering five experimentally determined flux distributions"
  Kousuke Maeda, Nobuyuki Okahashi, Yoshihiro Toya, Fumio Matsuda, Hiroshi Shimizu
  Metabolic Engineering Communications 3, -, 187-195 (2016).
• "Metabolome analysis of Saccharomyces cerevisiae and optimization of culture medium for S-adenosyl-L-methionine production"
  Kenshi Hayakawa, Fumio Matsuda, Hiroshi Shimizu
  AMB Express 6, 1, 44569 (2016).
• "Enhancement of 1,5-diaminopentane production in a recombinant strain of Corynebacterium glutamicum by Tween 40 addition"
  Yuta Matsushima, Takashi Hirasawa, Hiroshi Shimizu
  Journal of General and Applied Microbiology 62, 1, 42-45 (2016).

総説､解説

• "計算機シミュレーションを利用した代謝デザイン技術－有用物質生産の効率化を目的とした代謝経路の改変"
  戸谷 吉博
  化学と生物 (2016).
• "Recent advances in amino acid production by microbial cells"
  Takashi Hirasawa, Hiroshi Shimizu
  Current Opinion in Biotechnology 42, 133-146 (2016).

著書

• "Chapter 11. Glutamic acid fermentation: Discovery of glutamic acid-producing microorganisms, analysis of the production mechanism, metabolic engineering and industrial production process"
  Takashi Hirasawa, Hiroshi Shimizu
  BIOTECHNOLOGY, Wiley-VCH book series, Weinheim, Vol 4: Indsutrial Biotechnology Products and Processes, 339-360 (2016).