業績

2017年

原著論文

• "Identification of alcohol stress tolerance genes of Synechocystis sp. PCC 6803 by using adaptive laboratory evolution"
  Takuya Matsusako, Yoshihiro Toya, Katsunori Yoshikawa, Hiroshi Shimizu
  Biotechnology for Biofuels 10, 1, 307 (2017).
• "Prediction of cross-resistance and collateral sensitivity by gene expression profiles and genomic mutations"
  Takaaki Horinouchi, Shingo Suzuki, Hazuki Kotani, Kumi Tanabe, Natsue Sakata, Hiroshi Shimizu, Chikara Furusawa
  Scientific Report 7, 14009 (2017).
• "Metabolic engineering of isopropyl alcohol-producing Escherichia coli strains with 13C-metabolic flux analysis"
  Nobuyuki Okahashi, Fumio Matsuda, Katsunori Yoshikawa, Tomokazu Shirai, Yoshiko Matsumoto, Mitsufumi Wada, Hiroshi Shimizu
  Biotechnolgy and Bioengineering 114, 12, 2782-2793 (2017).
• "Heterologous expression of bacterial phosphoenol pyruvate carboxylase and Entner-Doudoroff pathway in Saccharomyces cerevisiae for improvement of isobutanol production"
  Keisuke Morita, Yuta Nomura, Jun Ishii, Fumio Matsuda, Akihiko Kondo, Hiroshi Shimizu
  Journal of Bioscience and Bioengineering 124, 3, 263-270 (2017).
• "The RB-IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity"
  Shunsuke Kitajima, Akiyo Yoshida, Susumu Kohno, Sawako Suzuki, Naoko Nagatani, Fengkai Li, Yuuki Nishimoto, Nobunari Sasaki, Hayato Muranaka, Yuansong Wan, Tran Thai, Nobuyuki Okahashi, Fumio Matsuda, Hiroshi Shimizu, Takumi Nishiuchi, Yutaka Suzuki, Kana Tominaga, Noriko Gotoh, Misa Suzuki, Mark Ewen, David Barbie, Osamu Hirose, Tomoaki Tanaka, Chiaki Takahashi
  Oncogene 36, 36, 5145-5157 (2017).
• "Metabolic impact of nutrient starvation in mevalonate-producing Escherichia coli"
  Ami Masuda, Yoshihiro Toya, Hiroshi Shimizu
  Bioresource Technology 245, Pt B, 1634-1640 (2017).
• "Prediction of hopeless peptides unlikely to be selected for targeted proteome analysis"
  Fumio Matsuda, Atsumi Tomita, Hiroshi Shimizu
  Mass Spectrometry 6, 1, A0056-A0056 (2017).
• "Targeted proteome analysis of single-gene deletion strains of Saccharomyces cerevisiae lacking enzymes in the central carbon metabolism"
  Fumio Matsuda, Syohei Kinoshita, Shunsuke Nishino, Atsumi Tomita, Hiroshi Shimizu
  PLoS One 12, 2, e0172742 (2017).
• "Metabolic engineering of Synechocystis sp. PCC 6803 for enhanced ethanol production based on flux balance analysis"
  Katsunori Yoshikawa, Yoshihiro Toya, Hiroshi Shimizu
  Bioprocess and Biosystems Engineering 40, 791-796 (2017).
• "Metabolic flux analysis of Synechocystis sp. PCC6803 ΔnrtABCD mutant reveals a mechanism for metabolic adaptation to nitrogen-limited conditions"
  Tsubasa Nakajima, Katsunori Yoshikawa, Yoshihiro Toya, Fumio Matsuda, Hiroshi Shimizu
  Plant and Cell Physiology 58, 3, 537-545 (2017).

総説､解説

• "Learning from quantitative data to understand central carbon metabolism"
  Fumio Matsuda, Yoshihiro Toya, Hiroshi Shimizu
  Biotechnology Advances 35, 8, 971-980 (2017).

学位論文

• "出芽酵母の代謝解析とその応用による物質生産性向上に関する研究"
  早川 謙嗣
  (2017).
• "遊離代謝物質に基づく物質生産大腸菌およびがん細胞の13C代謝フラックス解析に関する研究"
  岡橋 伸幸
  (2017).

著書

• "Chapter 7, Omics integrations for the state analysis of microbial processes"
  Hiroshi Shimizu, Chikara Fursawa, Takashi Hirasawa, Katsunori Yoshikawa, Yoshihiro Toya, Tomokazu Shirai, Fumio Matsuda
  BIOTECHNOLOGY, Wiley-VCH book series, Weinheim, Vol 5: Applied Bioengineering: Innovations and Future Directions, 201-236 (2017).
• "Chapter 8, Control of Microbial Processes"
  Kazuyuki Shimizu, Hiroshi Shimizu, Toshiomi Yoshida
  BIOTECHNOLOGY, Wiley-VCH book series, Weinheim, Vol 5: Applied Bioengineering: Innovations and Future Directions, 237- 258 (2017).