業績

2020年

原著論文

• "Novel allosteric inhibition of phosphoribulokinase identified by ensemble kinetic modeling of Synechocystis sp. PCC 6803 metabolism"
  Hiroki Nishiguchi, James Liao, Hiroshi Shimizu, Fumio Matsuda
  Metabolic Engineering Communications 11, e00153 (2020).
• "Estimation of linear and cyclic electron flows in photosynthesis based on 13C-metabolic flux analysis"
  Chiaki Yamamoto, Masakazu Toyoshima, Sayaka Kitamura, Yoshifumi Ueno, Seiji Akimoto, Yoshihiro Toya, Hiroshi Shimizu
  Journal of Bioscience and Bioengineering 131, 3, 277-282 (2020).
• "Identification of a rate-limiting step in a metabolic pathway using the kinetic model and in vitro experiment"
  Sayaka Kitamura, Hiroshi Shimizu, Yoshihiro Toya
  Journal of Bioscience and Bioengineering 131, 3, 271-276 (2020).

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• "Assessment of protein content and phosphorylation level in Synechocystis sp. PCC 6803 under various growth conditions using quantitative phosphoproteomic analysis"
  Masakazu Toyoshima, Yuma Tokumaru, Fumio Matsuda, Hiroshi Shimizu
  Molecules 25, 16, 3582 (2020).
• "Direct and quantitative analysis of altered metabolic flux distributions and cellular ATP production pathway in fumarate hydratase-diminished cells,"
  Shingo Noguchi, Hirokazu Ishikawa, Kenichi Wakita, Fumio Matsuda, Hiroshi Shimizu
  Scientific Reports 10, 1, 13065 (2020).
• "Data science-based modeling of the lysine fermentation process"
  Kento Tokuyama, Yoshiki Shimodaira, Takahiro Terawaki, Yasuhiro Kusunose, Hiroaki Nakai, Yuichiro Tsuji, Yoshihiro Toya, Fumio Matsuda, Hiroshi Shimizu
  Journal of Bioscience and Bioengineering 130, 4, 409-415 (2020).
• "Effects of mutations of GID protein-coding genes on malate production and enzyme expression profiles in Saccharomyces cerevisiae"
  Hiroaki Negoro, Kengo Matsumura, Fumio Matsuda, Hiroshi Shimizu, Yoji Hata, Hiroki Ishida
  Applied Microbiology and Biotechnology 102, 20, 8909-8920 (2020).
• "Transcription factor ArcA is a flux sensor for the oxygen consumption rate in Escherichia coli"
  Naoya Nochino, Yoshihiro Toya, Hiroshi Shimizu
  Biotechnology Journal 15, 6, e1900353 (2020).

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総説､解説

• "シアノバクテリア由来の光応答スイッチの大腸菌代謝工学への利用"
  戸谷 吉博
  生物工学会誌 98, 11, 608-610 (2020).
• "Flux controlling technology for central carbon metabolism for efficient microbial bio-production"
  Yoshihiro Toya, Hiroshi Shimizu
  Current Opinion in Biotechnology 64, 169-174 (2020).
• "光照射により代謝フラックスをコントロールする技術の開発"
  戸谷 吉博, 清水 浩
  バイオサイエンスとインダストリー 78, 1, 30-31 (2020).

学位論文

• "網羅的遺伝子発現解析を用いたシアノバクテリアの強光耐性機構に関する研究"
  小川 健一
  (2020).