業績

2025年

原著論文

• "Efficient selection of pyruvate decarboxylase sequences from database for high ethanol productivity in Synechocystis sp. PCC 6803"
  Hiroki Nishiguchi, Teppei Niide, Yoshihiro Toya, Hiroshi Shimizu
  Journal of Bioscience and Bioengineering (2025).

  • DOI: https://doi.org/10.1016/j.jbiosc.2025.05.011
• "Glycolaldehyde affects the growth of and metabolic flux distribution in Synechocystis sp. PCC 6803"
  Tatsumi Imada, Yoshihiro Toya, Hiroshi Shimizu
  Bioscience, Biotechnology, and Biochemistry (2025).

  • DOI: https://doi.org/10.1093/bbb/zbaf046
• "Engineering anaerobic electron flow through heterologous rhodoquinone synthesis in model microbial and photosynthetic platforms"
  Haruki Sasaki, Yuri Yanagihara, Yui Satofuka, Masaki Hasegawa, Yuichiro Kashiyama, Kimitoshi Sakamoto, Yoshihiro Toya, Hiroshi Shimizu, Takayuki Fujiwara, Shin’ya Miyagishima, Mitsuhiro Ueda, Tatsuji Sakamoto, Masami Nakazawa
  Journal of Bioscience and Bioengineering (2025).

  • DOI: https://doi.org/10.1016/j.jbiosc.2025.04.008
• "13C-metabolic flux analysis of respiratory chain disrupted strain ΔndhF1 of Synechocystis sp. PCC 6803 "
  Keisuke Wada, Yoshihiro Toya, Fumio Matsuda, Hiroshi Shimizu
  Applied Biochemistry and Biotechnology, in press (2025).

  • DOI: 10.1007/s12010-024-05138-4
• "Growth inhibition by ppc deletion is rescued by isocitrate dehydrogenase mutations in Escherichia coli"
  Yoshihiro Toya, Tatsumi Imada, Mai Ishibashi, Yuichi Kawamoto, Kinuka Isshiki, Atsushi Shibai, Chikara Furusawa, Hiroshi Shimizu
  FEMS Microbiology Letters 372, fnaf013 (2025).

  • DOI: 10.1093/femsle/fnaf013
• "Modification of intracellular metabolism by expression of a C-terminal variant of phosphoribulokinase from Synechocystis sp. PCC 6803"
  Hiroki Nishiguchi, Teppei Niide, Yoshihiro Toya, Hiroshi Shimizu
  Bioscience, Biotechnology, and Biochemistry, in press (2025).

  • DOI: 10.1093/bbb/zbaf013

著書

• "AIとバイオの融合最前線、（第4章８節代謝改変のための計算手法を援用した酵素基質特異性の調節と新機能開拓）"
  二井手哲平、戸谷吉博、清水浩
  CMC出版 (2025).